DCDT+ 2.3.4

DCDT+Oao is a WindowsT« program for analysis of sedimentation velocity (SV) data that implements the dc/dt method originally developed by Walter Stafford, and also implements fitting of the derived g(s*) distributions as a mixture containing of up t

DCDT+ 2.3.4

DCDT+Oao is a WindowsT« program for analysis of sedimentation velocity (SV) data that implements the dc/dt method originally developed by Walter Stafford, and also implements fitting of the derived g(s*) distributions as a mixture containing of up to 5 discrete (non-interacting) species.

The program is designed to be very easy to use, even for novices, yet it also offers many options for the 'power user' when they are needed. It uses multi-page analysis 'documents' and a familiar user interface with toolbars and buttons, making it similar to other Windows programs to reduce the learning curve. It also incorporates a number of intelligent 'wizards' that automatically accomplish tasks such as locating the meniscus position, removal of systematic noise ("jitter") and fringe jumps from interference scans, and even selection of which scans should be used for analysis.

This is not a package that tries to do everything---its purpose is to implement one particular approach, do that very well and very easily, and do it in a highly reproducible and well-documented manner.

The success of this approach is demonstrated by its use in 200+ publications. More significantly, many of these are from intermittent or casual users of AUC, proving you don't have to devote years to learning data analysis to successfully answer important research questions with SV.

The program is distributed as "trial-ware"; it can be downloaded for a 60-day free trial period.

Unique features:

- Modern multi-document, Explorer-style user interface
multiple analyses can be open simultaneously, and their g(s*) distributions are automatically incorporated into an overlay graph [example below]
- Explorer-like navigation tree to move to specific analysis pages (analysis steps) and between analysis documents
click-and-drag setting of meniscus marker, data limits, peak limits etc. [see image below]

- New algorithm for fitting of g(s*) distributions or dc/dt curves as mixtures gives s, D, and M values for each species with theoretical accuracy of better than 0.1%, independent of the number of scans used in the analysis
- Load the entire run and then use scroll bars to select the subset of scans to be analyzed (or just let the program wizard do it for you) [see image below]
- Optionally normalizes g(s*) distributions to allow easy comparisons of samples at different concentrations (a great diagnostic to distinguish interacting systems from mixtures, as in example shown 3 pictures above)
'Standard' program mode alters user interface to hide options you probably don't need; 'Advanced' mode provides more options to power users
- Program wizards automatically accomplish many tasks
Once scans are loaded, you can can calculate the g(s*) distribution and go all the way to a completed fit as a single species simply by repeatedly hitting the Enter key to accept the wizards' default choices
- New! Evaluates fitted parameter confidence intervals using any of three orthogonal approaches: F statistics, the bootstrap method, or a Monte Carlo algorithm that puts the random noise in the theoretical scans [to eliminate any concerns about effects of the transformation to g(s*)]
- True local Help file to give context-sensitive Help for each dialog box or control, with extensive tutorials and a searchable index. (A PDF file to print a user manual is also available to registered users)
- New! Generates nicely formatted printed reports with tables, and which document every factor that influences the results. These reports (with graphs) can be pasted into your word processor or electronic lab notebook
Saved analysis documents record every parameter, including the raw data, in a single file so you can re-load your analysis back to exactly the same state
Analysis documents appear in your 'My Recent Documents' folder, just like your other documents
Release notes: New Release
fixed problems with installation and registration
[ DCDT+ full changelog ]

   



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